node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
nrf1 | sirt1 | ENSDARP00000116798 | ENSDARP00000088981 | Nuclear respiratory factor 1; Probable transcription factor that is required for normal development of the outer retina. | Sirtuin 1. | 0.687 |
nrf1 | tfam | ENSDARP00000116798 | ENSDARP00000086442 | Nuclear respiratory factor 1; Probable transcription factor that is required for normal development of the outer retina. | Transcription factor A, mitochondrial. | 0.943 |
nrf1 | tfb1m | ENSDARP00000116798 | ENSDARP00000059657 | Nuclear respiratory factor 1; Probable transcription factor that is required for normal development of the outer retina. | rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. | 0.617 |
nrf1 | tfb2m | ENSDARP00000116798 | ENSDARP00000123820 | Nuclear respiratory factor 1; Probable transcription factor that is required for normal development of the outer retina. | rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. | 0.639 |
polg | polrmt | ENSDARP00000125000 | ENSDARP00000135213 | Polymerase (DNA directed), gamma. | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. | 0.829 |
polg | prkn | ENSDARP00000125000 | ENSDARP00000141580 | Polymerase (DNA directed), gamma. | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. | 0.524 |
polg | ssbp1 | ENSDARP00000125000 | ENSDARP00000057506 | Polymerase (DNA directed), gamma. | Single-stranded DNA-binding protein 1. | 0.858 |
polg | tfam | ENSDARP00000125000 | ENSDARP00000086442 | Polymerase (DNA directed), gamma. | Transcription factor A, mitochondrial. | 0.828 |
polg | tfb2m | ENSDARP00000125000 | ENSDARP00000123820 | Polymerase (DNA directed), gamma. | rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. | 0.411 |
polg | twnk | ENSDARP00000125000 | ENSDARP00000130722 | Polymerase (DNA directed), gamma. | Twinkle mtDNA helicase. | 0.940 |
polrmt | polg | ENSDARP00000135213 | ENSDARP00000125000 | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. | Polymerase (DNA directed), gamma. | 0.829 |
polrmt | ssbp1 | ENSDARP00000135213 | ENSDARP00000057506 | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. | Single-stranded DNA-binding protein 1. | 0.834 |
polrmt | tfam | ENSDARP00000135213 | ENSDARP00000086442 | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. | Transcription factor A, mitochondrial. | 0.998 |
polrmt | tfb1m | ENSDARP00000135213 | ENSDARP00000059657 | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. | rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. | 0.984 |
polrmt | tfb2m | ENSDARP00000135213 | ENSDARP00000123820 | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. | rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. | 0.999 |
polrmt | twnk | ENSDARP00000135213 | ENSDARP00000130722 | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. | Twinkle mtDNA helicase. | 0.858 |
prkn | polg | ENSDARP00000141580 | ENSDARP00000125000 | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. | Polymerase (DNA directed), gamma. | 0.524 |
prkn | sirt1 | ENSDARP00000141580 | ENSDARP00000088981 | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. | Sirtuin 1. | 0.583 |
prkn | tfam | ENSDARP00000141580 | ENSDARP00000086442 | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. | Transcription factor A, mitochondrial. | 0.770 |
prkn | tp53 | ENSDARP00000141580 | ENSDARP00000116736 | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression. | 0.577 |