node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
coq3 | fdft1 | ENSDARP00000031743 | ENSDARP00000141194 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | Farnesyl-diphosphate farnesyltransferase 1. | 0.409 |
coq3 | sqlea | ENSDARP00000031743 | ENSDARP00000098511 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | Squalene epoxidase a. | 0.854 |
coq3 | sqleb | ENSDARP00000031743 | ENSDARP00000086840 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | Squalene epoxidase b. | 0.854 |
cyp51 | dhcr7 | ENSDARP00000062550 | ENSDARP00000136120 | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. | 7-dehydrocholesterol reductase; Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC). | 0.990 |
cyp51 | fdft1 | ENSDARP00000062550 | ENSDARP00000141194 | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. | Farnesyl-diphosphate farnesyltransferase 1. | 0.996 |
cyp51 | hmgcs1 | ENSDARP00000062550 | ENSDARP00000137373 | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.991 |
cyp51 | lss | ENSDARP00000062550 | ENSDARP00000081675 | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.999 |
cyp51 | nsdhl | ENSDARP00000062550 | ENSDARP00000140493 | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. | NAD(P)-dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. | 0.993 |
cyp51 | sigmar1 | ENSDARP00000062550 | ENSDARP00000011354 | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. | Sigma non-opioid intracellular receptor 1; May function in lipid transport from the endoplasmic reticulum and be involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. May regulate calcium efflux at the endoplasmic reticulum (By similarity). | 0.979 |
cyp51 | sqlea | ENSDARP00000062550 | ENSDARP00000098511 | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. | Squalene epoxidase a. | 0.977 |
cyp51 | sqleb | ENSDARP00000062550 | ENSDARP00000086840 | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. | Squalene epoxidase b. | 0.934 |
cyp7a1b | dhcr7 | ENSDARP00000007208 | ENSDARP00000136120 | Uncharacterized protein. | 7-dehydrocholesterol reductase; Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC). | 0.936 |
cyp7a1b | fdft1 | ENSDARP00000007208 | ENSDARP00000141194 | Uncharacterized protein. | Farnesyl-diphosphate farnesyltransferase 1. | 0.707 |
cyp7a1b | hmgcs1 | ENSDARP00000007208 | ENSDARP00000137373 | Uncharacterized protein. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.566 |
cyp7a1b | lss | ENSDARP00000007208 | ENSDARP00000081675 | Uncharacterized protein. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.900 |
cyp7a1b | nsdhl | ENSDARP00000007208 | ENSDARP00000140493 | Uncharacterized protein. | NAD(P)-dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. | 0.561 |
cyp7a1b | sigmar1 | ENSDARP00000007208 | ENSDARP00000011354 | Uncharacterized protein. | Sigma non-opioid intracellular receptor 1; May function in lipid transport from the endoplasmic reticulum and be involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. May regulate calcium efflux at the endoplasmic reticulum (By similarity). | 0.691 |
cyp7a1b | sqlea | ENSDARP00000007208 | ENSDARP00000098511 | Uncharacterized protein. | Squalene epoxidase a. | 0.837 |
cyp7a1b | sqleb | ENSDARP00000007208 | ENSDARP00000086840 | Uncharacterized protein. | Squalene epoxidase b. | 0.903 |
dhcr7 | cyp51 | ENSDARP00000136120 | ENSDARP00000062550 | 7-dehydrocholesterol reductase; Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC). | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. | 0.990 |