STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100334911Ankyrin repeat and sterile alpha motif domain-containing 1Aa. (318 aa)    
Predicted Functional Partners:
anks4b
Ankyrin repeat and sterile alpha motif domain-containing 4B.
    
 
 0.840
mical1
[F-actin]-monooxygenase mical1; Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin to form methionine-sulfoxide, resulting in actin filament disassembly and prevent repolymerization; Belongs to the Mical family.
   
 
 0.759
rab11fip5a
RAB11 family-interacting protein 5a (class I).
   
  
 0.747
pkn3
Protein kinase N3.
    
 
 0.706
brk1
Probable protein BRICK1; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex (By similarity); Belongs to the BRK1 family.
    
 
 0.681
anks3
Ankyrin repeat and sterile alpha motif domain-containing 3.
    
 
 0.580
vwa8
Von Willebrand factor A domain-containing protein 8; Exhibits ATPase activity in vitro.
   
 
 0.565
bag4
BCL2-associated athanogene 4.
   
   0.544
nckap1
Nck-associated protein 1; Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1 (By similarity).
      
 0.541
srp19
Signal recognition particle 19.
   
    0.534
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.