STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clp1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Plays a role in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex: phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phospho [...] (443 aa)    
Predicted Functional Partners:
pcf11
PCF11 cleavage and polyadenylation factor subunit.
    
 0.999
cstf2
Cleavage stimulation factor, 3' pre-RNA, subunit 2.
   
 0.974
cstf3
Cleavage stimulation factor, 3' pre-RNA, subunit 3.
    
 0.961
cpsf3
Cleavage and polyadenylation-specific factor 3.
   
 0.935
gtf3c3
General transcription factor IIIC, polypeptide 3.
    
 
 0.934
cpsf4
Cleavage and polyadenylation-specific factor 4.
    
 0.914
fip1l1b
Pre-mRNA 3'-end-processing factor FIP1; Involved in mRNA processing; Belongs to the FIP1 family.
    
 0.910
cpsf2
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.907
tsen54
TSEN54 tRNA-splicing endonuclease subunit.
    
 0.891
cpsf1
Cleavage and polyadenylation-specific factor 1.
   
 0.890
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (24%) [HD]