STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pou3f2bPOU domain, class 3, transcription factor 2; Transcription factor that may play important roles in patterning the embryonic brain; Belongs to the POU transcription factor family. Class-3 subfamily. (378 aa)    
Predicted Functional Partners:
mms22l
Protein MMS22-like; Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks.
      
 0.645
sim1a
Single-minded homolog 1-A; Transcriptional factor that may have pleiotropic effects during embryogenesis and in the adult.
      
 0.636
nr2f1a
Nuclear receptor subfamily 2 group F member 1-A; Putative transcription factor that is required in photoreceptor cells precursors during eye development. Belongs to the nuclear hormone receptor family. NR2 subfamily.
   
 
 0.579
sim1b
SIM bHLH transcription factor 1b.
      
 0.564
foxp2
Forkhead box P2.
    
 
 0.546
olig2
Oligodendrocyte lineage transcription factor 2.
   
  
 0.531
oxt
Oxytocin; Belongs to the vasopressin/oxytocin family.
   
  
 0.531
sall2
Spalt-like transcription factor 2.
    
 
 0.512
arnt2
Aryl hydrocarbon receptor nuclear translocator 2; Transcription factor that plays a role in the development of the hypothalamo-pituitary axis. Specifically recognizes the xenobiotic response element (XRE) (By similarity). Isoform 1 acts as a transcriptional activator. Isoform 3 acts as a transcriptional repressor.
    
 
 0.502
myt1la
Myelin transcription factor 1-like, a.
   
  
 0.490
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.