STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tcf15Transcription factor 15. (183 aa)    
Predicted Functional Partners:
meox1
Homeobox protein MOX-1; Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints. Binds specifically to the promoter of target genes and regulates their expression. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome. Acts by med [...]
   
 
 0.756
fam110a
Family with sequence similarity 110 member A.
      
 0.743
tbx6
T-box transcription factor TBX6; T-box transcription factor involved in the development of paraxial mesoderm.
   
 
 0.645
meox2a
Mesenchyme homeobox 2a.
   
 
 0.618
tm2d2
TM2 domain-containing protein 2.
      
 0.596
tbx16l
T-box transcription factor TBX6L; Probable transcriptional regulator involved in developmental processes.
   
 
 0.596
uncx
Homeobox protein unc-4 homolog.
    
 
 0.524
irx3a
Iroquois 3 homeobox protein.
   
  
 0.480
zmat4b
Zinc finger, matrin-type 4b.
      
 0.479
uncx4.1
Homeobox protein unc-4 homolog; Transcription factor involved in somitogenesis and neurogenesis; Belongs to the paired homeobox family. Unc-4 subfamily.
    
 
 0.447
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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