STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
neurod6bNeurogenic differentiation factor 6-B; Differentiation factor required for neurogenesis (By similarity). Does not act as an upstream activator of isl1. (332 aa)    
Predicted Functional Partners:
znf296
Zinc finger protein 296.
    
 
 0.663
myt1la
Myelin transcription factor 1-like, a.
   
  
 0.635
tbr1a
T-box brain transcription factor 1a.
   
  
 0.607
tnrc18
Trinucleotide repeat-containing 18.
      
 0.601
aadat
Aminoadipate aminotransferase.
      
 0.587
insm1b
Insulinoma-associated protein 1b; May act as a transcriptional regulator. May play a role in neurogenesis and neuroendocrine cell differentiation during embryonic development (By similarity).
   
 
 0.563
ccnjl
Cyclin J-like; Belongs to the cyclin family.
   
  
 0.552
dmbx1b
Diencephalon/mesencephalon homeobox protein 1-B.
   
  
 0.523
slc17a6a
Vesicular glutamate transporter 2.2; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells.
   
  
 0.502
ghrhrb
Growth hormone-releasing hormone receptor b; Belongs to the G-protein coupled receptor 2 family.
   
  
 0.492
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.