STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ralgps1Ras-specific guanine nucleotide-releasing factor RalGPS1; Guanine nucleotide exchange factor. May be involved in cytoskeletal organization (581 aa)    
Predicted Functional Partners:
rabgef1l
RAB guanine nucleotide exchange factor (GEF) 1, like
   
  
 0.952
rabgef1
RAB guanine nucleotide exchange factor (GEF) 1
   
  
 0.952
ccbl1
Cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase)
   
  
 0.943
KYNU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family
      
 0.942
ENSDARG00000096343
Kynureninase
      
 0.942
RABGAP1
RAB GTPase activating protein 1
   
 
 0.717
crb2b
Crumbs homolog 2b
   
 
 0.692
garnl3
GTPase-activating Rap/Ran-GAP domain-like protein 3-like (garnl3), mRNA; Belongs to the GARNL3 family
   
  
 0.679
VWA3A
Von Willebrand factor A domain containing 3A
   
  
 0.587
crb2a
Crumbs homolog 2a
   
 
 0.574
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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