STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
neurod6aNeurogenic differentiation factor 6-A; Differentiation factor required for neurogenesis. Acts as an upstream activator of isl1. (327 aa)    
Predicted Functional Partners:
slitrk5a
SLIT and NTRK-like family, member 5a.
   
  
 0.672
creb1b
cAMP-responsive element-binding protein 1b.
      
 0.669
sez6a
Seizure-related 6 homolog a.
   
  
 0.589
grm2a
Glutamate receptor, metabotropic 2a.
   
  
 0.584
insm1b
Insulinoma-associated protein 1b; May act as a transcriptional regulator. May play a role in neurogenesis and neuroendocrine cell differentiation during embryonic development (By similarity).
   
 
 0.548
syt5b
Synaptotagmin Vb.
   
  
 0.529
meis2a
Meis homeobox 2a.
    
 
 0.501
klf7b
Kruppel-like factor 7 (Ubiquitous), like.
   
 
 0.488
lingo2a
Leucine-rich repeat and Ig domain-containing 2a.
   
  
 0.480
ephb2b
Eph receptor B2b.
      
 0.479
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.