node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
actr6 | h2az2a | ENSDARP00000005947 | ENSDARP00000090434 | Actin-related protein 6; Belongs to the actin family. | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] | 0.883 |
actr6 | ruvbl1 | ENSDARP00000005947 | ENSDARP00000012488 | Actin-related protein 6; Belongs to the actin family. | RuvB-like 1; Has single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity suggesting a role in nuclear processes such as recombination and transcription (By similarity). Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP- dependent nucleosome sliding (By similarity). May act as a negative regulator of embryonic heart growth. Belongs to the RuvB family. | 0.995 |
actr6 | srcap | ENSDARP00000005947 | ENSDARP00000127209 | Actin-related protein 6; Belongs to the actin family. | Snf2-related CREBBP activator protein. | 0.939 |
actr6 | yeats4 | ENSDARP00000005947 | ENSDARP00000067426 | Actin-related protein 6; Belongs to the actin family. | YEATS domain-containing 4. | 0.856 |
arid4a | h2ax1 | ENSDARP00000064411 | ENSDARP00000090794 | AT-rich interactive domain 4A (RBP1-like). | Histone H2A; Belongs to the histone H2A family. | 0.572 |
arid4a | h2az2a | ENSDARP00000064411 | ENSDARP00000090434 | AT-rich interactive domain 4A (RBP1-like). | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] | 0.903 |
arid4a | h3f3a-2 | ENSDARP00000064411 | ENSDARP00000089753 | AT-rich interactive domain 4A (RBP1-like). | Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] | 0.641 |
arid4a | hist2h2l | ENSDARP00000064411 | ENSDARP00000055912 | AT-rich interactive domain 4A (RBP1-like). | Histone H2B 3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.612 |
arid4a | ruvbl1 | ENSDARP00000064411 | ENSDARP00000012488 | AT-rich interactive domain 4A (RBP1-like). | RuvB-like 1; Has single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity suggesting a role in nuclear processes such as recombination and transcription (By similarity). Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP- dependent nucleosome sliding (By similarity). May act as a negative regulator of embryonic heart growth. Belongs to the RuvB family. | 0.629 |
arid4a | srcap | ENSDARP00000064411 | ENSDARP00000127209 | AT-rich interactive domain 4A (RBP1-like). | Snf2-related CREBBP activator protein. | 0.610 |
arid4a | yeats4 | ENSDARP00000064411 | ENSDARP00000067426 | AT-rich interactive domain 4A (RBP1-like). | YEATS domain-containing 4. | 0.743 |
arid4b | h2az2a | ENSDARP00000107839 | ENSDARP00000090434 | Translocase of outer mitochondrial membrane 20. | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] | 0.898 |
arid4b | h3f3a-2 | ENSDARP00000107839 | ENSDARP00000089753 | Translocase of outer mitochondrial membrane 20. | Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] | 0.619 |
arid4b | ruvbl1 | ENSDARP00000107839 | ENSDARP00000012488 | Translocase of outer mitochondrial membrane 20. | RuvB-like 1; Has single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity suggesting a role in nuclear processes such as recombination and transcription (By similarity). Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP- dependent nucleosome sliding (By similarity). May act as a negative regulator of embryonic heart growth. Belongs to the RuvB family. | 0.627 |
arid4b | srcap | ENSDARP00000107839 | ENSDARP00000127209 | Translocase of outer mitochondrial membrane 20. | Snf2-related CREBBP activator protein. | 0.587 |
arid4b | yeats4 | ENSDARP00000107839 | ENSDARP00000067426 | Translocase of outer mitochondrial membrane 20. | YEATS domain-containing 4. | 0.743 |
h2ax1 | arid4a | ENSDARP00000090794 | ENSDARP00000064411 | Histone H2A; Belongs to the histone H2A family. | AT-rich interactive domain 4A (RBP1-like). | 0.572 |
h2ax1 | h2az2a | ENSDARP00000090794 | ENSDARP00000090434 | Histone H2A; Belongs to the histone H2A family. | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] | 0.897 |
h2ax1 | h3f3a-2 | ENSDARP00000090794 | ENSDARP00000089753 | Histone H2A; Belongs to the histone H2A family. | Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] | 0.789 |
h2ax1 | hist2h2l | ENSDARP00000090794 | ENSDARP00000055912 | Histone H2A; Belongs to the histone H2A family. | Histone H2B 3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.919 |