STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
slc17a6bVesicular glutamate transporter 2.1; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. Required for glutamate release by retinotectal synapses and visual acuity. (584 aa)    
Predicted Functional Partners:
gad1b
Glutamate decarboxylase 1b.
   
 
 0.957
slc6a5
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
   
  
 0.931
gad2
Glutamate decarboxylase 2.
   
 
 0.893
elavl3
ELAV-like protein; Belongs to the RRM elav family.
   
  
 0.828
slc32a1
Solute carrier family 32 (GABA vesicular transporter), member 1.
   
  
 0.778
en1b
Homeobox protein engrailed-like.
      
 0.743
gad1a
Glutamate decarboxylase 1a.
   
 
 0.644
vsx2
Visual system homeobox 2; Acts as a transcriptional regulator (By similarity). Mediates the differentiation of V2a interneurons (By similarity). Plays a role in eye development and organization of the neuroretina.
      
 0.587
dbx1b
Homeobox protein DBX1-B; Belongs to the H2.0 homeobox family.
      
 0.585
hcrt
Hypocretin (orexin) neuropeptide precursor.
      
 0.585
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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