STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crybb1l3Crystallin, beta B1,-like 3; Belongs to the beta/gamma-crystallin family. (208 aa)    
Predicted Functional Partners:
gnb3a
Novel protein similar to guanine nucleotide binding protein (G protein) beta polypeptide family.
   
 
 0.679
guca1c
Guanylate cyclase-activating protein 3.
   
 
 0.677
cngb1a
Cyclic nucleotide-gated channel subunit beta 1a.
      
 0.661
cryaa
Crystallin, alpha A; Belongs to the small heat shock protein (HSP20) family.
   
  
 0.614
itsn2a
Intersectin 2a.
   
 
 0.592
pde6gb
Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b.
   
  
 0.589
itsn2b
Intersectin 2b.
    
 
 0.581
rdh8a
Photoreceptor associated retinol dehydrogenase type 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 
 0.577
itsn1
Intersectin 1 (SH3 domain protein).
    
 
 0.551
gngt2a
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.543
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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