STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tnfsf10lTNF superfamily member 10,-like; Belongs to the tumor necrosis factor family. (317 aa)    
Predicted Functional Partners:
tnfsf14
TNF superfamily member 14; Belongs to the tumor necrosis factor family.
      
 0.807
klhl10a
Kelch-like family member 10a.
      
 0.744
tnfsf18
TNF superfamily member 18; Belongs to the tumor necrosis factor family.
      
 0.695
tnfsf13b
TNF superfamily member 13b; Belongs to the tumor necrosis factor family.
      
 0.665
tnfsf12
Tumor necrosis factor superfamily member 12; Belongs to the tumor necrosis factor family.
   
  
 0.654
sept8b
Septin-8-B; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
      
 0.644
lta
Lymphotoxin alpha (TNF superfamily, member 1); Belongs to the tumor necrosis factor family.
      
 0.603
cyp11a2
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
   
  
 0.567
odf3b
Outer dense fiber protein 3-B.
   
  
 0.547
sept3
Neuronal-specific septin-3; May be involved in cytokinesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
      
 0.544
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.