STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ckmt2aCreatine kinase, mitochondrial 2a (sarcomeric); Belongs to the ATP:guanido phosphotransferase family. (417 aa)    
Predicted Functional Partners:
gamt
Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Important in nervous system development; Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
   
 
 0.921
E7EXM3_DANRE
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
      
 0.832
gdpd5b
Glycerophosphodiester phosphodiesterase domain-containing 5b.
      
 0.720
ckmt1
Creatine kinase, mitochondrial 1; Belongs to the ATP:guanido phosphotransferase family.
  
 
0.709
gdpd4a
Glycerophosphodiester phosphodiesterase domain-containing 4a.
      
 0.663
eno1b
Enolase 1b, (alpha).
  
 
 0.645
gdpd5a
Glycerophosphodiester phosphodiesterase domain-containing 5a.
      
 0.628
CLPB
ClpB homolog, mitochondrial AAA ATPase chaperonin.
  
 
 0.625
clpb
Caseinolytic mitochondrial matrix peptidase chaperone subunit B.
  
 
 0.625
myhb
Myosin, heavy chain b; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 
 0.615
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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