node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
E7EXN1_DANRE | popdc2 | ENSDARP00000098507 | ENSDARP00000092923 | Si:ch211-189k9.2. | Popeye domain-containing 2; Important for striated muscle differentiation and cardiac morphogenesis. Is also required for cardiac conduction system development, plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding. | 0.621 |
cav3 | kcnk2a | ENSDARP00000034317 | ENSDARP00000071906 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | Potassium channel, subfamily K, member 2a; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | 0.676 |
cav3 | kcnk2b | ENSDARP00000034317 | ENSDARP00000046437 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | Potassium channel, subfamily K, member 2b; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | 0.664 |
cav3 | popdc2 | ENSDARP00000034317 | ENSDARP00000092923 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | Popeye domain-containing 2; Important for striated muscle differentiation and cardiac morphogenesis. Is also required for cardiac conduction system development, plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding. | 0.622 |
cbr4 | popdc2 | ENSDARP00000010074 | ENSDARP00000092923 | Carbonyl reductase family member 4; The heterotetramer with HSD17B8 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis. Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD. The homotetramer has NADPH-dependent quinone reductase activity. Both homotetramer and the heterotetramer have broad in vitro substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o- quinones and p-quinones; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Popeye domain-containing 2; Important for striated muscle differentiation and cardiac morphogenesis. Is also required for cardiac conduction system development, plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding. | 0.589 |
hcn4 | kcnk2a | ENSDARP00000122248 | ENSDARP00000071906 | Hyperpolarization-activated cyclic nucleotide-gated potassium channel 4. | Potassium channel, subfamily K, member 2a; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | 0.525 |
hcn4 | kcnk2b | ENSDARP00000122248 | ENSDARP00000046437 | Hyperpolarization-activated cyclic nucleotide-gated potassium channel 4. | Potassium channel, subfamily K, member 2b; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | 0.517 |
hcn4 | popdc2 | ENSDARP00000122248 | ENSDARP00000092923 | Hyperpolarization-activated cyclic nucleotide-gated potassium channel 4. | Popeye domain-containing 2; Important for striated muscle differentiation and cardiac morphogenesis. Is also required for cardiac conduction system development, plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding. | 0.665 |
kcnk18 | popdc2 | ENSDARP00000074098 | ENSDARP00000092923 | Potassium channel, subfamily K, member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | Popeye domain-containing 2; Important for striated muscle differentiation and cardiac morphogenesis. Is also required for cardiac conduction system development, plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding. | 0.582 |
kcnk2a | cav3 | ENSDARP00000071906 | ENSDARP00000034317 | Potassium channel, subfamily K, member 2a; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | 0.676 |
kcnk2a | hcn4 | ENSDARP00000071906 | ENSDARP00000122248 | Potassium channel, subfamily K, member 2a; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | Hyperpolarization-activated cyclic nucleotide-gated potassium channel 4. | 0.525 |
kcnk2a | popdc2 | ENSDARP00000071906 | ENSDARP00000092923 | Potassium channel, subfamily K, member 2a; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | Popeye domain-containing 2; Important for striated muscle differentiation and cardiac morphogenesis. Is also required for cardiac conduction system development, plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding. | 0.919 |
kcnk2a | vamp3 | ENSDARP00000071906 | ENSDARP00000114025 | Potassium channel, subfamily K, member 2a; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | Vesicle-associated membrane protein 3 (Cellubrevin). | 0.582 |
kcnk2b | cav3 | ENSDARP00000046437 | ENSDARP00000034317 | Potassium channel, subfamily K, member 2b; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | 0.664 |
kcnk2b | hcn4 | ENSDARP00000046437 | ENSDARP00000122248 | Potassium channel, subfamily K, member 2b; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | Hyperpolarization-activated cyclic nucleotide-gated potassium channel 4. | 0.517 |
kcnk2b | popdc2 | ENSDARP00000046437 | ENSDARP00000092923 | Potassium channel, subfamily K, member 2b; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | Popeye domain-containing 2; Important for striated muscle differentiation and cardiac morphogenesis. Is also required for cardiac conduction system development, plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding. | 0.915 |
kcnk2b | vamp3 | ENSDARP00000046437 | ENSDARP00000114025 | Potassium channel, subfamily K, member 2b; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. | Vesicle-associated membrane protein 3 (Cellubrevin). | 0.622 |
mtus2a | popdc2 | ENSDARP00000084492 | ENSDARP00000092923 | Microtubule-associated tumor suppressor candidate 2a. | Popeye domain-containing 2; Important for striated muscle differentiation and cardiac morphogenesis. Is also required for cardiac conduction system development, plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding. | 0.667 |
popdc2 | E7EXN1_DANRE | ENSDARP00000092923 | ENSDARP00000098507 | Popeye domain-containing 2; Important for striated muscle differentiation and cardiac morphogenesis. Is also required for cardiac conduction system development, plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding. | Si:ch211-189k9.2. | 0.621 |
popdc2 | cav3 | ENSDARP00000092923 | ENSDARP00000034317 | Popeye domain-containing 2; Important for striated muscle differentiation and cardiac morphogenesis. Is also required for cardiac conduction system development, plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding. | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | 0.622 |