STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdpk1a3-phosphoinositide-dependent protein kinase 1a. (536 aa)    
Predicted Functional Partners:
rps6kb1a
Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
  
0.958
akt2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
0.958
rps6kb1b
Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
  
 
0.958
A3KQ53_DANRE
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
  
 
0.957
sgk1
Serine/threonine-protein kinase Sgk1; Protein kinase that may play an important role in cellular stress response. May be involved in the regulation of processes such as cell survival, neuronal excitability and renal sodium excretion (By similarity); Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
    
0.957
sgk2a
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
  
 
0.957
akt1
Non-specific serine/threonine protein kinase.
   
0.957
akt3b
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
0.956
akt3a
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
0.956
akt2l
V-akt murine thymoma viral oncogene homolog 2,-like.
   
0.956
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.