STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lman1Lectin, mannose-binding, 1. (513 aa)    
Predicted Functional Partners:
mcfd2
Multiple coagulation factor deficiency 2, ER cargo receptor complex subunit.
   
 0.999
sec22bb
Vesicle-trafficking protein SEC22b-B; SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
   
 0.897
fam110a
Family with sequence similarity 110 member A.
      
 0.806
tmed2
Transmembrane p24-trafficking protein 2.
   
 0.800
sec23a
Protein transport protein Sec23A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Belongs to the SEC23/SEC24 family. SEC23 subfamily.
   
 
 0.800
sec24c
SEC24 homolog C, COPII coat complex component.
   
 
 0.791
LOC100149700
Complexin 3a.
 
 
  
 0.777
gosr2
Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
   
 
 0.776
sec16b
SEC16 homolog B, endoplasmic reticulum export factor.
     
 0.770
cplx4a
Si:ch211-233a1.5.
 
 
  
 0.755
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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