STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
inka1bPAK4-inhibitor inka2; Inhibitor of the serine/threonine-protein kinase pak4/pak5. Acts by binding pak4/pak5 in a substrate-like manner, inhibiting the protein kinase activity. (288 aa)    
Predicted Functional Partners:
pak7
P21 protein (Cdc42/Rac)-activated kinase 7.
    
 
 0.737
suox
Sulfite oxidase.
      
 0.701
pak4
Non-specific serine/threonine protein kinase.
    
 
 0.675
trpm7
Transient receptor potential cation channel, subfamily M, member 7.
      
 0.644
LOC100536197
Non-specific serine/threonine protein kinase.
    
 
 0.543
pak6b
Non-specific serine/threonine protein kinase.
    
 
 0.543
ba1l
Ba1 globin, like.
      
 0.540
pak2b
Non-specific serine/threonine protein kinase.
    
 
 0.495
pak1
Non-specific serine/threonine protein kinase.
    
 
 0.495
pak2a
Non-specific serine/threonine protein kinase.
    
 
 0.495
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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