node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC100333141 | agbl5 | ENSDARP00000137975 | ENSDARP00000094377 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates tubulin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains. | 0.690 |
agbl4-2 | agbl5 | ENSDARP00000131925 | ENSDARP00000094377 | ATP/GTP-binding protein-like 4. | Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates tubulin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains. | 0.744 |
agbl5 | LOC100333141 | ENSDARP00000094377 | ENSDARP00000137975 | Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates tubulin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains. | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.690 |
agbl5 | agbl4-2 | ENSDARP00000094377 | ENSDARP00000131925 | Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates tubulin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains. | ATP/GTP-binding protein-like 4. | 0.744 |
agbl5 | b3galnt2 | ENSDARP00000094377 | ENSDARP00000067823 | Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates tubulin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains. | UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2; Beta-1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAc-beta-1-3GlcNAc, on N- and O- glycans. Has no galactose nor galactosaminyl transferase activity toward any acceptor substrate. Involved in alpha-dystroglycan (dag1) glycosylation; Belongs to the glycosyltransferase 31 family. | 0.560 |
agbl5 | crebzf | ENSDARP00000094377 | ENSDARP00000128064 | Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates tubulin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains. | CREB/ATF bZIP transcription factor. | 0.665 |
agbl5 | flr | ENSDARP00000094377 | ENSDARP00000055421 | Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates tubulin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains. | Tetratricopeptide repeat protein 30A; Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip (By similarity). Required for polyglutamylation of axonemal tubulin, which is a prerequisite for correct assembly of cilia and for normal cilia beat amplitude. Does not seem to be required for neuronal microtubule polyglutamylation. | 0.582 |
agbl5 | grinab | ENSDARP00000094377 | ENSDARP00000069140 | Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates tubulin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains. | Glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1b (glutamate-binding); Belongs to the BI1 family. | 0.571 |
agbl5 | ttl | ENSDARP00000094377 | ENSDARP00000113218 | Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates tubulin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains. | Tubulin tyrosine ligase. | 0.683 |
agbl5 | ttll1 | ENSDARP00000094377 | ENSDARP00000124463 | Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates tubulin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains. | Tubulin tyrosine ligase-like family, member 1. | 0.767 |
agbl5 | ttll3 | ENSDARP00000094377 | ENSDARP00000094767 | Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates tubulin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains. | Tubulin monoglycylase TTLL3; Monoglycylase which modifies alpha- and beta-tubulin, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Involved in the side-chain initiation step of the glycylation reaction by adding a single glycine chain to generate monoglycine side chains. Not involved in elongation step of the polyglycylation reaction (By similarity). | 0.650 |
agbl5 | ttll6 | ENSDARP00000094377 | ENSDARP00000124416 | Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates tubulin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains. | Tubulin polyglutamylase ttll6; Polyglutamylase which preferentially modifies alpha-tubulin. Mediates tubulin polyglutamylation in cilia. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step. Required for formation of olfactory cilia. Generates long side-chains (By similarity); Belongs to the tubulin--tyrosine ligase family. | 0.704 |
b3galnt2 | agbl5 | ENSDARP00000067823 | ENSDARP00000094377 | UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2; Beta-1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAc-beta-1-3GlcNAc, on N- and O- glycans. Has no galactose nor galactosaminyl transferase activity toward any acceptor substrate. Involved in alpha-dystroglycan (dag1) glycosylation; Belongs to the glycosyltransferase 31 family. | Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates tubulin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains. | 0.560 |
crebzf | agbl5 | ENSDARP00000128064 | ENSDARP00000094377 | CREB/ATF bZIP transcription factor. | Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates tubulin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains. | 0.665 |
crebzf | grinab | ENSDARP00000128064 | ENSDARP00000069140 | CREB/ATF bZIP transcription factor. | Glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1b (glutamate-binding); Belongs to the BI1 family. | 0.646 |
flr | agbl5 | ENSDARP00000055421 | ENSDARP00000094377 | Tetratricopeptide repeat protein 30A; Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip (By similarity). Required for polyglutamylation of axonemal tubulin, which is a prerequisite for correct assembly of cilia and for normal cilia beat amplitude. Does not seem to be required for neuronal microtubule polyglutamylation. | Cytosolic carboxypeptidase-like protein 5; Metallocarboxypeptidase that mediates tubulin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains. | 0.582 |
flr | ttl | ENSDARP00000055421 | ENSDARP00000113218 | Tetratricopeptide repeat protein 30A; Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip (By similarity). Required for polyglutamylation of axonemal tubulin, which is a prerequisite for correct assembly of cilia and for normal cilia beat amplitude. Does not seem to be required for neuronal microtubule polyglutamylation. | Tubulin tyrosine ligase. | 0.402 |
flr | ttll1 | ENSDARP00000055421 | ENSDARP00000124463 | Tetratricopeptide repeat protein 30A; Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip (By similarity). Required for polyglutamylation of axonemal tubulin, which is a prerequisite for correct assembly of cilia and for normal cilia beat amplitude. Does not seem to be required for neuronal microtubule polyglutamylation. | Tubulin tyrosine ligase-like family, member 1. | 0.475 |
flr | ttll3 | ENSDARP00000055421 | ENSDARP00000094767 | Tetratricopeptide repeat protein 30A; Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip (By similarity). Required for polyglutamylation of axonemal tubulin, which is a prerequisite for correct assembly of cilia and for normal cilia beat amplitude. Does not seem to be required for neuronal microtubule polyglutamylation. | Tubulin monoglycylase TTLL3; Monoglycylase which modifies alpha- and beta-tubulin, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Involved in the side-chain initiation step of the glycylation reaction by adding a single glycine chain to generate monoglycine side chains. Not involved in elongation step of the polyglycylation reaction (By similarity). | 0.745 |
flr | ttll6 | ENSDARP00000055421 | ENSDARP00000124416 | Tetratricopeptide repeat protein 30A; Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip (By similarity). Required for polyglutamylation of axonemal tubulin, which is a prerequisite for correct assembly of cilia and for normal cilia beat amplitude. Does not seem to be required for neuronal microtubule polyglutamylation. | Tubulin polyglutamylase ttll6; Polyglutamylase which preferentially modifies alpha-tubulin. Mediates tubulin polyglutamylation in cilia. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step. Required for formation of olfactory cilia. Generates long side-chains (By similarity); Belongs to the tubulin--tyrosine ligase family. | 0.807 |