STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nap1l4aNucleosome assembly protein 1-like 4a; Belongs to the nucleosome assembly protein (NAP) family. (349 aa)    
Predicted Functional Partners:
slc22a18
Solute carrier family 22 member 18.
      
 0.861
osbpl5
Oxysterol-binding protein; Belongs to the OSBP family.
 
    
 0.860
phlda2
Pleckstrin homology-like domain family A member 2; Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids (By similarity).
   
  
 0.848
nptxra
Neuronal pentraxin receptor a.
      
 0.807
cbx6b
Chromobox homolog 6b.
      
 0.806
h2az2a
Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...]
   
 
 0.776
rps6
40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.
   
 
 0.764
h2az2b
Histone H2A; Belongs to the histone H2A family.
   
 
 0.759
arl15a
ADP-ribosylation factor-like 15a.
    
 
 0.753
tssc4
Protein TSSC4; Belongs to the TSSC4 family.
      
 0.751
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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