STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
l1camaNeural cell adhesion molecule L1.2; Cell adhesion molecule with an important role in the development of the nervous system. Involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Binds to axonin on neurons (By similarity); Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family. (1271 aa)    
Predicted Functional Partners:
ncam2
Neural cell adhesion molecule 2.
   
0.936
Zgc:152904
Zgc:152904.
   
0.935
ncam1b
Neural cell adhesion molecule 1b.
   
0.930
ca16b
Carbonic anhydrase XVI b.
   
 
 0.577
ptprga
Protein tyrosine phosphatase receptor type g a.
   
 
 0.565
mvp
Major vault protein; Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport (By similarity).
      
 0.540
cntn1a
Contactin-1a.
   
 
0.538
cntn2
Contactin 2.
   
 
0.451
hps1
HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.
      
 0.438
sema4d
Uncharacterized protein; Belongs to the semaphorin family.
    
 
 0.423
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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