STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppp4caSerine/threonine-protein phosphatase 4 catalytic subunit A; Protein phosphatase that regulates many processes such as microtubule organization at centrosomes; Belongs to the PPP phosphatase family. PP-4 (PP-X) subfamily. (311 aa)    
Predicted Functional Partners:
igbp1
Immunoglobulin (CD79A)-binding protein 1.
   
 
 0.934
ppp4r1l
Protein phosphatase 4, regulatory subunit 1-like.
   
 
 0.903
doc2a
Double C2-like domains, alpha.
      
 0.899
kif22
Kinesin-like protein KIF22; Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA.
   
 
 0.889
ptpa
Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
   
 
 0.874
smek1
Serine/threonine-protein phosphatase 4 regulatory subunit 3; Regulatory subunit of serine/threonine-protein phosphatase 4. Belongs to the SMEK family.
   
 
 0.870
ypel3
Protein yippee-like 3; May be involved in proliferation and apoptosis in myeloid precursor cells; Belongs to the yippee family.
   
  
 0.868
prrt2
Proline-rich transmembrane protein 2.
    
 
 0.868
asphd1
Aspartate beta-hydroxylase domain-containing 1.
      
 0.860
ppp4r2a
Serine/threonine-protein phosphatase 4 regulatory subunit 2-A; Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4C); Belongs to the PPP4R2 family.
   
 
 0.857
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.