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fezf2 protein (Danio rerio) - STRING interaction network
"fezf2" - Fez family zinc finger protein 2 in Danio rerio
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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fezf2Fez family zinc finger protein 2; Transcription repressor. Component of the regulatory cascade that controls the development of dopaminergic (DA) and serotonergic (5HT) neurons (438 aa)    
Predicted Functional Partners:
tbr1b
T-box, brain, 1b (676 aa)
     
 
  0.868
otpa
Orthopedia homolog a (332 aa)
     
 
  0.856
otpb
Homeobox protein orthopedia B; Involved in the specification of isotocin cells. Required for the specification of dopaminergic neurons in the developing hypothalamus and posterior tuberculum (328 aa)
     
 
  0.855
satb2
DNA-binding protein SATB; SATB homeobox 2 (834 aa)
     
 
  0.844
neurog1
Neurogenin-1; Transcriptional regulator. Activates transcription by binding to the E box-containing promoter (By similarity). Mediates neuronal differentiation. Required for the development of Rohon- Beard spinal sensory neurons and dorsal root ganglion neurons, but not for primary motoneurons or autonomic neurons. Required for development of all cranial ganglia but not associated glial cells. Regulates epiphysial neurogenesis, acting partially redundantly with ascl1a and downstream of flh. Required for the development of basal forebrain dopaminergic neurons; involved in the specificat [...] (208 aa)
     
 
  0.743
otx2
Homeobox protein OTX2; May play a role in very early embryogenesis, gastrulation, and the development and subdivision of the diencephalon and the midbrain (289 aa)
     
 
  0.717
cux2
Cut-like homeobox 2b (1353 aa)
     
 
  0.709
sox5
SRY (sex determining region Y)-box 5; SRY-box containing gene 5 (759 aa)
     
 
  0.701
cdx1a
Caudal type homeo box transcription factor 1 a (112 aa)
       
 
  0.696
irx1b
Iroquois homeobox protein 1, b (445 aa)
       
 
  0.687
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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