STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dyrk4Dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 4. (634 aa)    
Predicted Functional Partners:
dcaf7
Ddb1 and cul4-associated factor 7.
   
 
 0.805
nrip2
Nuclear receptor-interacting protein 2.
      
 0.762
rnf169
E3 ubiquitin-protein ligase RNF169; Probable E3 ubiquitin-protein ligase that acts as a negative regulator of double-strand breaks (DSBs) repair following DNA damage.
   
 
 0.687
tspan11
Tetraspanin.
      
 0.647
tspan9a
Tetraspanin.
   
  
 0.552
tspan9b
Tetraspanin-9.
      
 0.550
ddb1
Damage-specific DNA-binding protein 1.
    
 
 0.483
rap1b
Ras-related protein Rap-1b; Probable GTP-binding protein that possesses GTPase activity. May play a role in endothelial cell polarity and endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family.
    
 
 0.460
fkbp4
Peptidylprolyl isomerase.
      
 0.442
rap1aa
RAP1A, member of RAS oncogene family a.
    
 
 0.436
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.