| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ASS1 | aldh18a1 | ENSDARP00000140635 | ENSDARP00000137162 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.798 |
| ASS1 | asl | ENSDARP00000140635 | ENSDARP00000040189 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | Argininosuccinate lyase. | 0.999 |
| ASS1 | oat | ENSDARP00000140635 | ENSDARP00000125055 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.989 |
| ASS1 | otc | ENSDARP00000140635 | ENSDARP00000083959 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.997 |
| ASS1 | pm20d1.2 | ENSDARP00000140635 | ENSDARP00000095363 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | N-fatty-acyl-amino acid synthase/hydrolase PM20D1.2; Bidirectional N-fatty-acyl amino acid synthase/hydrolase that regulates the production of N-fatty-acyl amino acids. These metabolites are endogenous chemical uncouplers of mitochondrial respiration. In an UCP1-independent manner, maybe through interaction with mitochondrial transporters, they promote proton leakage into the mitochondrial matrix. Thereby, this secreted protein may indirectly regulate the bodily dissipation of chemical energy as heat through thermogenic respiration; Belongs to the peptidase M20A family. | 0.814 |
| ASS1 | psat1 | ENSDARP00000140635 | ENSDARP00000022134 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | Phosphoserine aminotransferase. | 0.836 |
| aldh18a1 | ASS1 | ENSDARP00000137162 | ENSDARP00000140635 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | 0.798 |
| aldh18a1 | asl | ENSDARP00000137162 | ENSDARP00000040189 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Argininosuccinate lyase. | 0.852 |
| aldh18a1 | oat | ENSDARP00000137162 | ENSDARP00000125055 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.997 |
| aldh18a1 | otc | ENSDARP00000137162 | ENSDARP00000083959 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.702 |
| aldh18a1 | pm20d1.2 | ENSDARP00000137162 | ENSDARP00000095363 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | N-fatty-acyl-amino acid synthase/hydrolase PM20D1.2; Bidirectional N-fatty-acyl amino acid synthase/hydrolase that regulates the production of N-fatty-acyl amino acids. These metabolites are endogenous chemical uncouplers of mitochondrial respiration. In an UCP1-independent manner, maybe through interaction with mitochondrial transporters, they promote proton leakage into the mitochondrial matrix. Thereby, this secreted protein may indirectly regulate the bodily dissipation of chemical energy as heat through thermogenic respiration; Belongs to the peptidase M20A family. | 0.775 |
| aldh18a1 | psat1 | ENSDARP00000137162 | ENSDARP00000022134 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Phosphoserine aminotransferase. | 0.896 |
| asl | ASS1 | ENSDARP00000040189 | ENSDARP00000140635 | Argininosuccinate lyase. | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. | 0.999 |
| asl | aldh18a1 | ENSDARP00000040189 | ENSDARP00000137162 | Argininosuccinate lyase. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.852 |
| asl | oat | ENSDARP00000040189 | ENSDARP00000125055 | Argininosuccinate lyase. | Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.998 |
| asl | otc | ENSDARP00000040189 | ENSDARP00000083959 | Argininosuccinate lyase. | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.965 |
| asl | pm20d1.2 | ENSDARP00000040189 | ENSDARP00000095363 | Argininosuccinate lyase. | N-fatty-acyl-amino acid synthase/hydrolase PM20D1.2; Bidirectional N-fatty-acyl amino acid synthase/hydrolase that regulates the production of N-fatty-acyl amino acids. These metabolites are endogenous chemical uncouplers of mitochondrial respiration. In an UCP1-independent manner, maybe through interaction with mitochondrial transporters, they promote proton leakage into the mitochondrial matrix. Thereby, this secreted protein may indirectly regulate the bodily dissipation of chemical energy as heat through thermogenic respiration; Belongs to the peptidase M20A family. | 0.537 |
| asl | psat1 | ENSDARP00000040189 | ENSDARP00000022134 | Argininosuccinate lyase. | Phosphoserine aminotransferase. | 0.696 |
| dpyda.1 | oat | ENSDARP00000137932 | ENSDARP00000125055 | Dihydropyrimidine dehydrogenase a, tandem duplicate 1. | Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.404 |
| dpyda.1 | pm20d1.2 | ENSDARP00000137932 | ENSDARP00000095363 | Dihydropyrimidine dehydrogenase a, tandem duplicate 1. | N-fatty-acyl-amino acid synthase/hydrolase PM20D1.2; Bidirectional N-fatty-acyl amino acid synthase/hydrolase that regulates the production of N-fatty-acyl amino acids. These metabolites are endogenous chemical uncouplers of mitochondrial respiration. In an UCP1-independent manner, maybe through interaction with mitochondrial transporters, they promote proton leakage into the mitochondrial matrix. Thereby, this secreted protein may indirectly regulate the bodily dissipation of chemical energy as heat through thermogenic respiration; Belongs to the peptidase M20A family. | 0.528 |