STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
abhd12Lysophosphatidylserine lipase ABHD12; Lysophosphatidylserine (LPS) lipase that mediates the hydrolysis of lysophosphatidylserine, a class of signaling lipids that regulates immunological and neurological processes (By similarity). Represents a major lysophosphatidylserine lipase in the brain, thereby playing a key role in the central nervous system (By similarity). Also able to hydrolyze oxidized phosphatidylserine; oxidized phosphatidylserine is produced in response to severe inflammatory stress and constitutes a proapoptotic 'eat me' signal. Also has monoacylglycerol (MAG) lipase act [...] (382 aa)    
Predicted Functional Partners:
abhd6a
Abhydrolase domain-containing 6a.
  
  
 0.909
napepld
N-acyl phosphatidylethanolamine phospholipase D.
     
 0.889
abhd16a
Abhydrolase domain-containing 16A.
      
 0.872
abhd4
Abhydrolase domain-containing 4.
  
  
 0.831
abhd6b
Abhydrolase domain-containing 6b.
  
  
 0.815
faah
Fatty acid amide hydrolase.
   
  
 0.808
faah2a
Fatty-acid amide hydrolase 2-A.
   
  
 0.755
gde1
Glycerophosphodiester phosphodiesterase 1.
     
 0.721
abhd3
Abhydrolase domain-containing 3.
      
 0.690
auh
AU RNA-binding protein/enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
      
 0.675
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (28%) [HD]