STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
chchd3bMICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (449 aa)    
Predicted Functional Partners:
trim35-9
Tripartite motif-containing 35-9.
      
 0.999
slc25a48
Solute carrier family 25 member 48.
   
 
 0.942
csad
Cysteine sulfinic acid decarboxylase.
   
  
 0.886
immt
MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
   
 0.863
bckdk
Protein-serine/threonine kinase.
   
  
 0.835
cyp2k6
Cytochrome P450 2K6; Metabolizes aflatoxin B1 (AFB1) to the cytotoxic derivative AFB1 exo-8,9-epoxide. Does not show activity towards lauric acid.
      
 0.834
cyp2k31
Cytochrome P450 2K6; Belongs to the cytochrome P450 family.
      
 0.833
adra2c
Alpha-2C adrenergic receptor; Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The order of potency for this receptor is dexmedetomidine > norepinephrine > epinephrine; Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2C sub-subfamily.
      
 0.831
hsd17b3
Hydroxysteroid (17-beta) dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.736
apoob
MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
   
 0.715
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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