STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tle5TLE family member 5, transcriptional modulator. (197 aa)    
Predicted Functional Partners:
tmem9b
TMEM9 domain family, member B.
      
 0.564
gak
Cyclin G-associated kinase.
    
 
 0.558
tcf7l2
Transcription factor 7-like 2 (T-cell specific, HMG-box).
    
 
 0.551
PAQR9
Progestin and adipoQ receptor family member 9.
      
 0.540
tcea3
Transcription elongation factor A (SII), 3.
      
 0.533
lef1
Lymphocyte enhancer binding factor 1 Lef1.
    
 
 0.528
en1b
Homeobox protein engrailed-like.
    
 
 0.524
tbx20
T-box transcription factor TBX20; Transcriptional regulator that may play a very early role in the differentiation of the cardiac precursors.
    
 
 0.501
tcf7l1b
Transcription factor 7-like 1-B; Participates in the Wnt signaling pathway. Probably binds to DNA and acts as a repressor in the absence of ctnnb1, and possibly as an activator in its presence. Regulates anterior-posterior patterning in the neuroectoderm by repressing posterior neural fates. Also required for hindbrain morphogenesis. Belongs to the TCF/LEF family.
    
 
 0.497
her6
Hairy-related 6.
    
 
 0.465
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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