STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lrrc39Leucine-rich repeat-containing protein 39; Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress (By similarity). May regulate expression of other M-band proteins via an SRF-dependent pathway (By similarity). Important for normal contractile function in heart. (343 aa)    
Predicted Functional Partners:
rtca
RNA terminal phosphate cyclase domain 1.
    
 
 0.870
dbt
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
      
 0.861
trmt13
tRNA methyltransferase 13 homolog.
      
 0.814
ppp1r42
Protein phosphatase 1 regulatory subunit 42; May regulate phosphatase activity of protein phosphatase 1 (PP1) complexes.
    
 
 0.812
tnni2b.1
Troponin I type 2b (skeletal, fast), tandem duplicate 1.
   
  
 0.759
trim101
Tripartite motif-containing 101.
   
 
 0.739
dph5
Diphthamide biosynthesis 5.
      
 0.701
asb16
Ankyrin repeat and SOCS box-containing 16.
   
 
 0.689
lrrc14b
Leucine-rich repeat-containing protein 14B; Belongs to the PRAME family. LRRC14 subfamily.
   
  
 0.687
asb12a
Ankyrin repeat and SOCS box-containing 12a.
   
 
 0.669
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.