STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nav3Neuron navigator 3; May be involved in neuron regeneration; Belongs to the Nav/unc-53 family. (2269 aa)    
Predicted Functional Partners:
ppfia2
PTPRF-interacting protein alpha 2.
   
 
 0.754
kcnc2
Potassium voltage-gated channel, Shaw-related subfamily, member 2; Belongs to the potassium channel family.
   
 
 0.679
tenm1
Teneurin transmembrane protein 1.
    
 
 0.647
wnt2bb
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 
 0.644
syt10
Synaptotagmin X.
    
 
 0.625
gys2
Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.
    
 
 0.546
Aunip
Si:ch1073-228h2.2.
      
 0.545
VASH1
Vasohibin 1.
    
 
 0.484
snapc2
Small nuclear RNA-activating complex, polypeptide 2.
   
  
 0.481
tenm3
Teneurin-3; Involved in neural development by regulating the establishment of proper connectivity within the nervous system. Acts in both pre- and postsynaptic neurons in the hippocampus to control the assembly of a precise topographic projection: required in both CA1 and subicular neurons for the precise targeting of proximal CA1 axons to distal subiculum, probably by promoting homophilic cell adhesion (By similarity). Required by retinal ganglion cells for acquisition of their correct morphological and functional connectivity, thereby playing a key role in the development of the visu [...]
   
 
 0.471
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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