STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C10H5orf30Macrophage immunometabolism regulator; May play a role in immune regulation through regulation of the macrophage function (By similarity). Involved in the recruitment of macrophages in response to injury. May also play a role in trafficking of proteins via its interaction with unc119 family cargo adapters (By similarity). May play a role in ciliary membrane localization. (206 aa)    
Predicted Functional Partners:
SPDEF
SAM pointed domain containing ETS transcription factor.
    
   0.557
unc119a
Unc-119 homolog a (C. elegans).
    
 
 0.531
unc119b
Protein unc-119 homolog B.
    
 
 0.531
unc119.2
Unc-119 lipid-binding chaperone B homolog 2.
    
 
 0.420
ENSDARP00000157013
GMP_PDE_delta domain-containing protein.
    
 
 0.420
trmt11
tRNA methyltransferase 11 homolog.
      
 0.408
unc119.1
Protein unc-119 homolog B; Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Plays a key role in localization of proteins to the primary cilium membrane. Belongs to the PDE6D/unc-119 family.
    
 
 0.405
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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