STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
csnk2bCasein kinase II subunit beta; Participates in Wnt signaling. Plays a complex role in regulating the basal catalytic activity of the alpha subunit (By similarity). (215 aa)    
Predicted Functional Partners:
csnk2a1
Casein kinase 2, alpha 1 polypeptide; Belongs to the protein kinase superfamily.
   
 0.969
csnk2a2a
Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily.
   
 0.969
rrp7a
Ribosomal RNA-processing 7 homolog A.
    
 
 0.948
csnk2a2b
Casein kinase 2, alpha prime polypeptide b; Belongs to the protein kinase superfamily.
   
 0.943
csnk2a4
Casein kinase 2, alpha 4 polypeptide; Belongs to the protein kinase superfamily.
   
 0.942
supt16h
SPT16 homolog, facilitates chromatin-remodeling subunit.
   
  0.935
ctnnb1
Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...]
   
 0.935
nol6
Nucleolar protein 6.
   
 
 0.930
zgc:86598
Zgc:86598; Belongs to the protein kinase superfamily.
   
 0.915
wdr36
WD repeat domain 36.
   
 
 0.914
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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