Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RNF122 | RNF5 | ENSDARP00000139712 | ENSDARP00000099944 | Si:ch1073-392o20.1. | Ring finger protein 5. | 0.698 |
| RNF122 | erlin1 | ENSDARP00000139712 | ENSDARP00000015815 | Si:ch1073-392o20.1. | Erlin-1; Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex; Belongs to the band 7/mec-2 family. | 0.444 |
| RNF122 | mavs | ENSDARP00000139712 | ENSDARP00000080716 | Si:ch1073-392o20.1. | Mitochondrial antiviral-signaling protein. | 0.574 |
| RNF122 | trim13 | ENSDARP00000139712 | ENSDARP00000013495 | Si:ch1073-392o20.1. | Tripartite motif-containing 13; E3 ubiquitin ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD). This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins (By similarity). | 0.729 |
| RNF5 | RNF122 | ENSDARP00000099944 | ENSDARP00000139712 | Ring finger protein 5. | Si:ch1073-392o20.1. | 0.698 |
| RNF5 | abhd16a | ENSDARP00000099944 | ENSDARP00000103741 | Ring finger protein 5. | Abhydrolase domain-containing 16A. | 0.751 |
| RNF5 | cftr | ENSDARP00000099944 | ENSDARP00000060242 | Ring finger protein 5. | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | 0.729 |
| RNF5 | derl1 | ENSDARP00000099944 | ENSDARP00000036613 | Ring finger protein 5. | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | 0.730 |
| RNF5 | erlin1 | ENSDARP00000099944 | ENSDARP00000015815 | Ring finger protein 5. | Erlin-1; Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex; Belongs to the band 7/mec-2 family. | 0.653 |
| RNF5 | erlin2 | ENSDARP00000099944 | ENSDARP00000121177 | Ring finger protein 5. | Erlin-2; Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Promotes sterol-accelerated ERAD of HMGCR. Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway (By similarity); Belongs to the band 7/mec-2 family. | 0.653 |
| RNF5 | mavs | ENSDARP00000099944 | ENSDARP00000080716 | Ring finger protein 5. | Mitochondrial antiviral-signaling protein. | 0.733 |
| RNF5 | rnf26 | ENSDARP00000099944 | ENSDARP00000102151 | Ring finger protein 5. | Ring finger protein 26. | 0.785 |
| RNF5 | sel1l | ENSDARP00000099944 | ENSDARP00000007196 | Ring finger protein 5. | SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. | 0.697 |
| RNF5 | trim13 | ENSDARP00000099944 | ENSDARP00000013495 | Ring finger protein 5. | Tripartite motif-containing 13; E3 ubiquitin ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD). This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins (By similarity). | 0.661 |
| abhd16a | RNF5 | ENSDARP00000103741 | ENSDARP00000099944 | Abhydrolase domain-containing 16A. | Ring finger protein 5. | 0.751 |
| cftr | RNF5 | ENSDARP00000060242 | ENSDARP00000099944 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | Ring finger protein 5. | 0.729 |
| cftr | derl1 | ENSDARP00000060242 | ENSDARP00000036613 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | 0.763 |
| cftr | erlin1 | ENSDARP00000060242 | ENSDARP00000015815 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | Erlin-1; Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex; Belongs to the band 7/mec-2 family. | 0.499 |
| cftr | erlin2 | ENSDARP00000060242 | ENSDARP00000121177 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | Erlin-2; Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Promotes sterol-accelerated ERAD of HMGCR. Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway (By similarity); Belongs to the band 7/mec-2 family. | 0.499 |
| cftr | sel1l | ENSDARP00000060242 | ENSDARP00000007196 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. | 0.581 |
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