STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tlr8bToll-like receptor 8b. (802 aa)    
Predicted Functional Partners:
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response.
    
 0.941
tlr8a
Toll-like receptor 8a; Belongs to the Toll-like receptor family.
  
  
0.918
tlr7
Toll-like receptor 7; Belongs to the Toll-like receptor family.
  
  
 
0.906
tlr20.2
Toll-like receptor 20, tandem duplicate 2.
      
 0.644
prf1.2
Perforin 1.2.
    
 
 0.563
ddx41
DEAD (Asp-Glu-Ala-Asp) box polypeptide 41.
   
 
 0.553
ly86
Lymphocyte antigen 86.
   
 
 0.536
E7FB32_DANRE
Si:zfos-323e3.4.
  
 
   0.507
unc93b1
Unc-93 homolog B1, TLR-signaling regulator.
    
 
 0.501
il15
Interleukin; Belongs to the IL-15/IL-21 family.
      
 0.480
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.