STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dlx5aHomeobox protein Dlx5a; Belongs to the distal-less homeobox family. (282 aa)    
Predicted Functional Partners:
edn1
Endothelin 1.
   
  
 0.706
ednraa
Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.691
hand2
Heart- and neural crest derivatives-expressed protein 2; Essential for myocardial and pectoral fin differentiation, patterning and morphogenesis.
   
  
 0.688
dlx6a
Homeobox protein Dlx6a.
   
  
0.667
lhx6
LIM homeobox 6.
   
  
 0.610
sox9a
HMG box transcription factor Sox9a.
   
 
 0.597
myf6
Myogenic factor 6; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein (By similarity).
   
  
 0.561
ednrab
Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.552
lhx8a
LIM homeobox 8a.
   
  
 0.537
sox10
HMG-box transcription factor Sox10.
   
 
 0.524
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.