STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100333265G_PROTEIN_RECEP_F1_2 domain-containing protein. (377 aa)    
Predicted Functional Partners:
f2
Coagulation factor II (thrombin); Belongs to the peptidase S1 family.
    
 0.939
F2RL3
Si:ch211-132p1.2; Belongs to the G-protein coupled receptor 1 family.
     
 
0.800
plg
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
    
  0.685
zgc:92590
Zgc:92590; Belongs to the peptidase S1 family.
    
  0.685
prss1
Serine protease 1; Belongs to the peptidase S1 family.
    
  0.685
prss59.2
Serine protease 59, tandem duplicate 2; Belongs to the peptidase S1 family.
    
  0.685
X1WC94_DANRE
Si:dkeyp-93a5.2; Belongs to the peptidase S1 family.
    
  0.685
zmp:0000001088
Zmp:0000001088; Belongs to the peptidase S1 family.
    
  0.685
LOC560023
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
  0.658
E7FCZ0_DANRE
Si:dkey-33m11.8; Belongs to the peptidase S1 family.
    
  0.658
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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