STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
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[Homology]
Score
slc7a2Cationic amino acid transporter 2; Low-affinity, high capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine). Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family. (640 aa)    
Predicted Functional Partners:
mrpl45
Mitochondrial ribosomal protein L45.
      
 0.675
slc43a1a
Solute carrier family 43 member 1a.
      
 0.634
ASS1
Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family.
    
 
 0.607
slc38a4
Solute carrier family 38 member 4.
   
  
 0.606
kcnc2
Potassium voltage-gated channel, Shaw-related subfamily, member 2; Belongs to the potassium channel family.
   
  
 0.598
arf3a
ADP-ribosylation factor 3a; Belongs to the small GTPase superfamily. Arf family.
   
 
 0.585
adar
Adenosine deaminase RNA-specific.
   
  
 0.583
pip5kl1
Phosphatidylinositol-4-phosphate 5-kinase-like 1.
      
 0.583
mboat1
Membrane-bound O-acyltransferase domain-containing 1; Belongs to the membrane-bound acyltransferase family.
    
 
 0.577
ppp1r9bb
Protein phosphatase 1, regulatory subunit 9Bb.
    
 
 0.560
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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