node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CLPB | clpb | ENSDARP00000110209 | ENSDARP00000127613 | ClpB homolog, mitochondrial AAA ATPase chaperonin. | Caseinolytic mitochondrial matrix peptidase chaperone subunit B. | 0.422 |
CLPB | dnajc10 | ENSDARP00000110209 | ENSDARP00000103524 | ClpB homolog, mitochondrial AAA ATPase chaperonin. | DnaJ (Hsp40) homolog, subfamily C, member 10. | 0.702 |
CLPB | dnajc2 | ENSDARP00000110209 | ENSDARP00000094239 | ClpB homolog, mitochondrial AAA ATPase chaperonin. | DnaJ homolog subfamily C member 2; Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription ac [...] | 0.565 |
CLPB | grpel1 | ENSDARP00000110209 | ENSDARP00000026495 | ClpB homolog, mitochondrial AAA ATPase chaperonin. | GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. | 0.900 |
CLPB | grpel2 | ENSDARP00000110209 | ENSDARP00000091810 | ClpB homolog, mitochondrial AAA ATPase chaperonin. | GrpE-like 2, mitochondrial; Belongs to the GrpE family. | 0.867 |
CLPB | hsp90aa1.1 | ENSDARP00000110209 | ENSDARP00000022302 | ClpB homolog, mitochondrial AAA ATPase chaperonin. | Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] | 0.694 |
CLPB | hsp90aa1.2 | ENSDARP00000110209 | ENSDARP00000026065 | ClpB homolog, mitochondrial AAA ATPase chaperonin. | Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. | 0.650 |
CLPB | hsp90ab1 | ENSDARP00000110209 | ENSDARP00000014978 | ClpB homolog, mitochondrial AAA ATPase chaperonin. | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | 0.650 |
CLPB | stip1 | ENSDARP00000110209 | ENSDARP00000100503 | ClpB homolog, mitochondrial AAA ATPase chaperonin. | Stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein). | 0.860 |
CLPB | tmem59 | ENSDARP00000110209 | ENSDARP00000105109 | ClpB homolog, mitochondrial AAA ATPase chaperonin. | Si:dkey-181m9.10 protein. | 0.714 |
clpb | CLPB | ENSDARP00000127613 | ENSDARP00000110209 | Caseinolytic mitochondrial matrix peptidase chaperone subunit B. | ClpB homolog, mitochondrial AAA ATPase chaperonin. | 0.422 |
clpb | dnajc10 | ENSDARP00000127613 | ENSDARP00000103524 | Caseinolytic mitochondrial matrix peptidase chaperone subunit B. | DnaJ (Hsp40) homolog, subfamily C, member 10. | 0.702 |
clpb | grpel1 | ENSDARP00000127613 | ENSDARP00000026495 | Caseinolytic mitochondrial matrix peptidase chaperone subunit B. | GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. | 0.854 |
clpb | grpel2 | ENSDARP00000127613 | ENSDARP00000091810 | Caseinolytic mitochondrial matrix peptidase chaperone subunit B. | GrpE-like 2, mitochondrial; Belongs to the GrpE family. | 0.854 |
clpb | hsp90aa1.1 | ENSDARP00000127613 | ENSDARP00000022302 | Caseinolytic mitochondrial matrix peptidase chaperone subunit B. | Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] | 0.673 |
clpb | hsp90aa1.2 | ENSDARP00000127613 | ENSDARP00000026065 | Caseinolytic mitochondrial matrix peptidase chaperone subunit B. | Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. | 0.626 |
clpb | hsp90ab1 | ENSDARP00000127613 | ENSDARP00000014978 | Caseinolytic mitochondrial matrix peptidase chaperone subunit B. | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | 0.626 |
clpb | stip1 | ENSDARP00000127613 | ENSDARP00000100503 | Caseinolytic mitochondrial matrix peptidase chaperone subunit B. | Stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein). | 0.522 |
clpb | tmem59 | ENSDARP00000127613 | ENSDARP00000105109 | Caseinolytic mitochondrial matrix peptidase chaperone subunit B. | Si:dkey-181m9.10 protein. | 0.675 |
dnajc10 | CLPB | ENSDARP00000103524 | ENSDARP00000110209 | DnaJ (Hsp40) homolog, subfamily C, member 10. | ClpB homolog, mitochondrial AAA ATPase chaperonin. | 0.702 |