STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
roraaNuclear receptor ROR-alpha A; Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) (By similarity). Required for proper cerebellum development. (468 aa)    
Predicted Functional Partners:
ncor2
Nuclear receptor corepressor 2.
    
 0.699
cry1b
Cryptochrome circadian regulator 1b.
    
 
 0.686
cry1a
Cryptochrome circadian regulator 1a.
    
 
 0.674
nr2e3
Nuclear receptor subfamily 2, group E, member 3.
    
0.670
arntl1a
Aryl hydrocarbon receptor nuclear translocator-like 1a.
    
 
 0.665
hoxa9b
Homeobox protein Hox-A9b; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Abd-B homeobox family.
      
 0.626
per1a
Period circadian clock 1a.
    
 
 0.626
arntl1b
Aryl hydrocarbon receptor nuclear translocator-like 1b.
    
 
 0.622
clocka
Clock circadian regulator a.
   
 
 0.600
prkrip1
PRKR-interacting protein 1 homolog; Required for pre-mRNA splicing as component of the spliceosome (By similarity). Binds double-stranded RNA (By similarity).
      
 0.598
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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