STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lamb4Laminin subunit beta-4; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. (1827 aa)    
Predicted Functional Partners:
cd44b
CD44 molecule (Indian blood group) b.
     
  0.900
icn2
Protein S100; Belongs to the S-100 family.
   
  
 0.746
fat1b
FAT atypical cadherin 1b.
      
 0.742
vwde
Von Willebrand factor D and EGF domains.
   
  
 0.725
itgb4
Integrin beta.
   
 
 0.714
itgav
Integrin, alpha V; Belongs to the integrin alpha chain family.
     
 0.712
itga2.2
Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2; Belongs to the integrin alpha chain family.
   
 
 0.707
itgb3a
Integrin beta; Belongs to the integrin beta chain family.
     
 0.706
itga11a
Integrin, alpha 11a; Belongs to the integrin alpha chain family.
   
 
 0.701
itga1
Integrin, alpha 1; Belongs to the integrin alpha chain family.
   
 
 0.701
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.