node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CACNA2D1 | cacna1aa | ENSDARP00000151934 | ENSDARP00000023232 | Si:dkey-266j7.2. | Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a. | 0.737 |
CACNA2D1 | cacna1ab | ENSDARP00000151934 | ENSDARP00000133186 | Si:dkey-266j7.2. | Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b. | 0.669 |
CACNA2D1 | cacna1c | ENSDARP00000151934 | ENSDARP00000116425 | Si:dkey-266j7.2. | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. | 0.949 |
CACNA2D1 | cacna1da | ENSDARP00000151934 | ENSDARP00000137557 | Si:dkey-266j7.2. | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. | 0.870 |
CACNA2D1 | cacna1e | ENSDARP00000151934 | ENSDARP00000084404 | Si:dkey-266j7.2. | Calcium channel, voltage-dependent, R type, alpha 1E subunit a. | 0.841 |
CACNA2D1 | cacna1fb | ENSDARP00000151934 | ENSDARP00000041563 | Si:dkey-266j7.2. | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. | 0.753 |
CACNA2D1 | cacnb1 | ENSDARP00000151934 | ENSDARP00000057158 | Si:dkey-266j7.2. | Calcium channel, voltage-dependent, beta 1 subunit. | 0.944 |
CACNA2D1 | cacng1a | ENSDARP00000151934 | ENSDARP00000028126 | Si:dkey-266j7.2. | Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. | 0.864 |
CACNA2D1 | cacng1b | ENSDARP00000151934 | ENSDARP00000068688 | Si:dkey-266j7.2. | Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. | 0.812 |
CACNA2D1 | stac3 | ENSDARP00000151934 | ENSDARP00000133228 | Si:dkey-266j7.2. | SH3 and cysteine-rich domain-containing protein 3; Required for normal excitation-contraction coupling in skeletal muscle and for normal muscle contraction in response to membrane depolarization. Required for normal Ca(2+) release from the sarcplasmic reticulum, which ultimately leads to muscle contraction. Probably functions via its effects on muscle calcium channels. Increases CACNA1S channel activity, in addition to its role in enhancing the expression of CACNA1S at the cell membrane. Has a redundant role in promoting the expression of the calcium channel CACNA1S at the cell membran [...] | 0.540 |
cacna1aa | CACNA2D1 | ENSDARP00000023232 | ENSDARP00000151934 | Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a. | Si:dkey-266j7.2. | 0.737 |
cacna1aa | cacna1ab | ENSDARP00000023232 | ENSDARP00000133186 | Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a. | Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b. | 0.556 |
cacna1aa | cacna1c | ENSDARP00000023232 | ENSDARP00000116425 | Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a. | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. | 0.652 |
cacna1aa | cacna1da | ENSDARP00000023232 | ENSDARP00000137557 | Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a. | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. | 0.674 |
cacna1aa | cacna1e | ENSDARP00000023232 | ENSDARP00000084404 | Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a. | Calcium channel, voltage-dependent, R type, alpha 1E subunit a. | 0.579 |
cacna1aa | cacna1fb | ENSDARP00000023232 | ENSDARP00000041563 | Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a. | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. | 0.667 |
cacna1aa | cacnb1 | ENSDARP00000023232 | ENSDARP00000057158 | Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a. | Calcium channel, voltage-dependent, beta 1 subunit. | 0.823 |
cacna1aa | cacng1a | ENSDARP00000023232 | ENSDARP00000028126 | Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a. | Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. | 0.862 |
cacna1aa | cacng1b | ENSDARP00000023232 | ENSDARP00000068688 | Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a. | Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. | 0.823 |
cacna1aa | stac3 | ENSDARP00000023232 | ENSDARP00000133228 | Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a. | SH3 and cysteine-rich domain-containing protein 3; Required for normal excitation-contraction coupling in skeletal muscle and for normal muscle contraction in response to membrane depolarization. Required for normal Ca(2+) release from the sarcplasmic reticulum, which ultimately leads to muscle contraction. Probably functions via its effects on muscle calcium channels. Increases CACNA1S channel activity, in addition to its role in enhancing the expression of CACNA1S at the cell membrane. Has a redundant role in promoting the expression of the calcium channel CACNA1S at the cell membran [...] | 0.544 |