STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
afap1Actin filament-associated protein 1. (806 aa)    
Predicted Functional Partners:
gas7a
Growth arrest-specific 7a.
      
 0.839
gmds
GDP-mannose 4,6 dehydratase.
      
 0.817
lrp12
Low density lipoprotein receptor-related protein 12.
      
 0.766
tmco1
Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling, thereby playing a key role in calcium homeostasis. In response to endoplasmic reticulum overloading, assembles into a homotetramer, forming a functional calcium-selective channel, regulating the calcium content in endoplasmic reticulum store (By similarity); Belongs to the TMCO1 family.
      
 0.740
tgfbr3
Transforming growth factor, beta receptor III.
      
 0.690
srbd1
S1 RNA-binding domain 1.
      
 0.628
SRBD1
Si:ch211-117n7.8.
      
 0.628
nhlrc2
NHL repeat-containing 2.
    
 
 0.608
asb10
Ankyrin repeat and SOCS box-containing 10.
      
 0.558
ENSDARP00000117118
Thioredoxin reductase 2, tandem duplicate 1.
      
 0.542
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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