STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rhogdRas homolog gene family, member Ga. (191 aa)    
Predicted Functional Partners:
X1WBN8_DANRE
Si:dkey-56f14.7.
    
 0.936
elmo1
Engulfment and Cell motility 1 (Ced-12 homolog, C. elegans).
    
 0.936
itsn2a
Intersectin 2a.
    
 
 0.791
itsn2b
Intersectin 2b.
    
 
 0.791
itsn1
Intersectin 1 (SH3 domain protein).
    
 
 0.761
nrsn1l
Neurensin 1-like.
      
 0.700
rp1l1b
Rp1-like 1b.
      
 0.697
mosmob
Modulator of smoothened protein; Acts as a negative regulator of hedgehog signaling probably by promoting internalization and subsequent degradation of smoothened protein (SMO) present in the ciliary membrane. Plays a role in sonic hedgehog (SHH)-induced spinal neural progenitor cells differentiation.
      
 0.670
lrrc15
Leucine-rich repeat-containing 15.
    
 
 0.669
lingo2a
Leucine-rich repeat and Ig domain-containing 2a.
    
 
 0.668
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.