Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cactin | cdc40 | ENSDARP00000078145 | ENSDARP00000060431 | Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family. | Cell division cycle 40 homolog (S. cerevisiae). | 0.914 |
| cactin | cwc22 | ENSDARP00000078145 | ENSDARP00000013971 | Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family. | Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly. | 0.963 |
| cactin | fam32a | ENSDARP00000078145 | ENSDARP00000108572 | Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family. | Protein FAM32A-like; May induce G2 arrest and apoptosis. May also increase cell sensitivity to apoptotic stimuli; Belongs to the FAM32 family. | 0.987 |
| cactin | nkap | ENSDARP00000078145 | ENSDARP00000001288 | Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family. | NFKB activating protein-like. | 0.952 |
| cactin | ppil1 | ENSDARP00000078145 | ENSDARP00000127620 | Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family. | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.910 |
| cactin | prkrip1 | ENSDARP00000078145 | ENSDARP00000045517 | Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family. | PRKR-interacting protein 1 homolog; Required for pre-mRNA splicing as component of the spliceosome (By similarity). Binds double-stranded RNA (By similarity). | 0.991 |
| cactin | sde2 | ENSDARP00000078145 | ENSDARP00000043773 | Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family. | Replication stress response regulator SDE2; Involved in both DNA replication and cell cycle control. Unprocessed SDE2 interacts with PCNA via its PIP-box. The interaction with PCNA prevents monoubiquitination of the latter thereby inhibiting translesion DNA synthesis. The binding of SDE2 to PCNA also leads to processing of SDE2 by an unidentified deubiquitinating enzyme, cleaving off the N-terminal ubiquitin-like domain. The resulting mature SDE2 is degraded by the DCX(DTL) complex in a cell cycle- and DNA damage dependent manner. Binding of SDE2 to PCNA is necessary to counteract dama [...] | 0.986 |
| cactin | slu7 | ENSDARP00000078145 | ENSDARP00000112935 | Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family. | Pre-mRNA-splicing factor SLU7; Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. | 0.969 |
| cactin | syf2 | ENSDARP00000078145 | ENSDARP00000090723 | Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family. | Pre-mRNA-splicing factor syf2; Involved in pre-mRNA splicing as component of the spliceosome. | 0.915 |
| cactin | yju2 | ENSDARP00000078145 | ENSDARP00000035484 | Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family. | Splicing factor YJU2; Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates (By similarity). May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex ; Belongs to the CWC16 family. YJU2 subfamily. | 0.646 |
| cdc40 | cactin | ENSDARP00000060431 | ENSDARP00000078145 | Cell division cycle 40 homolog (S. cerevisiae). | Cactin; May be involved in the regulation of innate immune response (By similarity). Plays a role during early embryonic development. Involved in the formation of the anteroposterior axis with important roles also in neural development; Belongs to the CACTIN family. | 0.914 |
| cdc40 | cwc22 | ENSDARP00000060431 | ENSDARP00000013971 | Cell division cycle 40 homolog (S. cerevisiae). | Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly. | 0.998 |
| cdc40 | fam32a | ENSDARP00000060431 | ENSDARP00000108572 | Cell division cycle 40 homolog (S. cerevisiae). | Protein FAM32A-like; May induce G2 arrest and apoptosis. May also increase cell sensitivity to apoptotic stimuli; Belongs to the FAM32 family. | 0.918 |
| cdc40 | nkap | ENSDARP00000060431 | ENSDARP00000001288 | Cell division cycle 40 homolog (S. cerevisiae). | NFKB activating protein-like. | 0.897 |
| cdc40 | ppil1 | ENSDARP00000060431 | ENSDARP00000127620 | Cell division cycle 40 homolog (S. cerevisiae). | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.989 |
| cdc40 | prkrip1 | ENSDARP00000060431 | ENSDARP00000045517 | Cell division cycle 40 homolog (S. cerevisiae). | PRKR-interacting protein 1 homolog; Required for pre-mRNA splicing as component of the spliceosome (By similarity). Binds double-stranded RNA (By similarity). | 0.963 |
| cdc40 | sde2 | ENSDARP00000060431 | ENSDARP00000043773 | Cell division cycle 40 homolog (S. cerevisiae). | Replication stress response regulator SDE2; Involved in both DNA replication and cell cycle control. Unprocessed SDE2 interacts with PCNA via its PIP-box. The interaction with PCNA prevents monoubiquitination of the latter thereby inhibiting translesion DNA synthesis. The binding of SDE2 to PCNA also leads to processing of SDE2 by an unidentified deubiquitinating enzyme, cleaving off the N-terminal ubiquitin-like domain. The resulting mature SDE2 is degraded by the DCX(DTL) complex in a cell cycle- and DNA damage dependent manner. Binding of SDE2 to PCNA is necessary to counteract dama [...] | 0.976 |
| cdc40 | slu7 | ENSDARP00000060431 | ENSDARP00000112935 | Cell division cycle 40 homolog (S. cerevisiae). | Pre-mRNA-splicing factor SLU7; Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. | 0.993 |
| cdc40 | syf2 | ENSDARP00000060431 | ENSDARP00000090723 | Cell division cycle 40 homolog (S. cerevisiae). | Pre-mRNA-splicing factor syf2; Involved in pre-mRNA splicing as component of the spliceosome. | 0.999 |
| cdc40 | yju2 | ENSDARP00000060431 | ENSDARP00000035484 | Cell division cycle 40 homolog (S. cerevisiae). | Splicing factor YJU2; Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates (By similarity). May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex ; Belongs to the CWC16 family. YJU2 subfamily. | 0.994 |
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