STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
desi1bPPPDE peptidase domain containing 2b. (167 aa)    
Predicted Functional Partners:
uspl1
SUMO-specific isopeptidase USPL1; SUMO-specific isopeptidase involved in protein desumoylation. Specifically binds SUMO proteins with a higher affinity for sumo2 and sumo3 which it cleaves more efficiently. Also able to process full- length SUMO proteins to their mature forms. Plays a key role in RNA polymerase-II-mediated snRNA transcription in the Cajal bodies (By similarity). Is a component of complexes that can bind to U snRNA genes (By similarity).
      
 0.880
psmc4
Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.
   
   0.859
psmd8
Proteasome 26S subunit, non-ATPase 8.
   
   0.857
psmc3
Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.
   
   0.857
psmc5
Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family.
   
   0.857
psma5
Proteasome subunit alpha type.
   
   0.856
psmc2
Proteasome (Prosome, macropain) 26S subunit, ATPase 2; Belongs to the AAA ATPase family.
   
   0.856
psmb1
Proteasome subunit beta.
    
   0.856
psmb3
Proteasome subunit beta.
    
   0.856
psma4
Proteasome subunit alpha type.
    
   0.856
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.