STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cul1aCullin 1a; Belongs to the cullin family. (777 aa)    
Predicted Functional Partners:
skp1
S-phase kinase-associated protein 1A; Belongs to the SKP1 family.
   
 0.999
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.999
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.
    
 0.996
fbxw11b
F-box and WD repeat domain-containing 11b.
   
 0.987
cand1
Cullin-associated and neddylation-dissociated 1.
   
 0.985
nedd8
NEDD8 ubiquitin-like modifier.
    
 0.973
cdk2
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.
    
 0.957
ccne1
G1/S-specific cyclin-E1; Essential for the control of the cell cycle at the G1/S (start) transition; Belongs to the cyclin family. Cyclin E subfamily.
    
 0.949
nedd8l
NEDD8 ubiquitin-like modifier, like.
    
 
 0.948
fbxl17
F-box and leucine-rich repeat protein 17.
    
 0.943
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.