STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ngrnNeugrin, neurite outgrowth-associated. (289 aa)    
Predicted Functional Partners:
caly
Calcyon neuron-specific vesicular protein.
      
 0.807
fastkd2
FAST kinase domains 2.
   
 
 0.799
sh3bgrl2
SH3 domain-binding glutamic acid-rich-like protein 2.
      
 0.749
rundc3ab
RUN domain-containing protein 3A.
      
 0.745
mxd4
MAX dimerization protein 4.
    
 
 0.739
bcas2
Pre-mRNA-splicing factor SPF27; Required for pre-mRNA splicing as component of the activated spliceosome. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex.
      
 0.695
trub2
TruB pseudouridine (psi) synthase family member 2.
    
 
 0.695
camta2
Calmodulin-binding transcription activator 2.
      
 0.680
rpusd4
Mitochondrial RNA pseudouridine synthase rpusd4; Converts specific uridines to pseudouridine (PSI) in different mitochondrial RNA substrates. Acts on 16S mitochondrial ribosomal RNA (16S mt-rRNA). This modification is required for the assembly of 16S mt-rRNA into a functional mitochondrial ribosome. Acts on mitochondrial tRNA(Phe).
    
 
 0.673
rps6kal
Ribosomal protein S6 kinase alpha-6; Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
   
  
 0.669
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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