STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpc7aTransient receptor potential cation channel, subfamily C, member 7a; Belongs to the transient receptor (TC 1.A.4) family. (842 aa)    
Predicted Functional Partners:
cacng3a
Calcium channel, voltage-dependent, gamma subunit 3a.
   
  
 0.818
trpm1b
Transient receptor potential cation channel, subfamily M, member 1b.
    
0.622
cacna1e
Calcium channel, voltage-dependent, R type, alpha 1E subunit a.
   
  
 0.584
trpc1
Transient receptor potential cation channel, subfamily C, member 1; Belongs to the transient receptor (TC 1.A.4) family.
  
 
0.562
cacnb1
Calcium channel, voltage-dependent, beta 1 subunit.
      
 0.544
trpm7
Transient receptor potential cation channel, subfamily M, member 7.
    
 0.509
trpa1a
Transient receptor potential cation channel, subfamily A, member 1a.
   
 
 0.502
trpm2
Transient receptor potential cation channel subfamily M member 2; Nonselective, voltage-independent cation channel that mediates Ca(2+) influx, leading to increased cytoplasmic Ca(2+) levels. Functions as ligand-gated ion channel. Binding of ADP-ribose to the cytoplasmic N-terminal region causes a conformation change; the channel is primed but still requires Ca(2+) binding to trigger channel opening. Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM2 sub-subfamily.
    
0.500
trpc5a
Transient receptor potential cation channel, subfamily C, member 5a; Belongs to the transient receptor (TC 1.A.4) family.
  
0.482
trpc4b
Transient receptor potential cation channel, subfamily C, member 4b; Belongs to the transient receptor (TC 1.A.4) family.
  
 
0.478
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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