STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rusc2RUN and SH3 domain-containing 2. (920 aa)    
Predicted Functional Partners:
rusc1
RUN and SH3 domain-containing 1.
 
    
 0.985
serinc1
Serine incorporator 1.
      
 0.815
rab35b
RAB35, member RAS oncogene family b.
    
 
 0.757
TESK1
Si:ch211-113e8.3.
    
 
 0.746
idi1
Isopentenyl-diphosphate delta isomerase 1.
  
 
 0.746
mvda
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes; Belongs to the diphosphomevalonate decarboxylase family.
  
 0.745
fdft1
Farnesyl-diphosphate farnesyltransferase 1.
  
 0.731
atg9a
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
    
 
 0.717
ap4e1
AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.
      
 0.716
ap4b1
AP complex subunit beta; Belongs to the adaptor complexes large subunit family.
   
  
 0.672
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.