STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmeff2aTransmembrane protein with EGF-like and two follistatin-like domains 2a. (379 aa)    
Predicted Functional Partners:
stk17b
Serine/threonine kinase 17B (Apoptosis-inducing); Belongs to the protein kinase superfamily.
      
 0.742
rprd1a
Regulation of nuclear pre-mRNA domain-containing 1A.
      
 0.669
cavin2a
Caveolae-associated protein 2a.
      
 0.668
elp2
Elongator complex protein 2; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs; Belongs to the WD repeat ELP2 family.
      
 0.629
slc23a2
Solute carrier family 23 member 2.
      
 0.621
mapkap1
MAPK-associated protein 1.
      
 0.596
lamb1a
Laminin, beta 1a.
     
 0.573
cdh13
Cadherin 13, H-cadherin (heart).
   
  
 0.570
rassf2a
Ras association domain family member 2a.
      
 0.557
rassf2b
Ras association domain family member 2b.
      
 0.556
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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